A serious crash on a major Melbourne freeway has sparked long traffic delays.

On Tuesday at about 1pm, a car rolled on the Eastlink in Scoresby and has ended up on its roof.

The number of people involved in the crash and injuries are not yet known.

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There are four fire trucks, police vehicles and an ambulance on the scene.

Three southbound lanes are closed between Ferntree Gully and Wellington Rd and delays are building rapidly.

Drivers have been urged to consider exiting the freeway at Ferntree Gully Rd or earlier.

More to come …